He leido este articulo en SmartBrief (MMRF).

cita:

"Comparison of whole-body MR imaging and conventional X-ray examination in patients with multiple myeloma and implications for therapy."
Dinter DJ, Neff WK, Klaus J, B?hm C, Hastka J, Weiss C, Schoenberg SO, Metzgeroth G.

Department of Clinical Radiology and Nuclear Medicine, University Medical Center Manheim, Mannheim, Germany, .

Skeletal X-ray survey is the established method of diagnosis in patients with multiple myeloma; however, whole-body magnetic resonance imaging (wb-MRI) has become an important additional tool. The aim of this study was to compare the different patterns of infiltration on conventional X-ray examinations (X-ray survey) with findings from wb-MRI to subsequently determine the influence of wb-MRI on therapy changes. In 60 patients with a mean age of 65.1 +/- 11.7 years, wb-MRI examinations were correlated with a recent X-ray survey. The results were independently assessed by two radiologists and the patterns of infiltration were described in both modalities. Subsequently, the disease was staged according to Salmon and Durie and Salmon and Durie PLUS. Additionally, the influence of MRI on potential changes in therapy was assessed using a three-range Likert-type scale. In all, 480 skeletal regions were compared. In 183 skeletal regions, an increased degree of infiltration was identified on wb-MRI. Significant differences (p < 0.05) between the modalities could be found in the thorax, spine, pelvis, and both lower extremities. Based on wb-MRI, tumor stage was upgraded in 19 of the 60 patients using the Durie and Salmon PLUS classification. In ten out of these 19 patients (42%), the wb-MRI result was essential for making the decision to initiate further therapy due to the degree of infiltration, extramedullary tumor extension, and/or further risk of fracture.
 Whole-body MRI provides a more detailed assessment of the pattern of bone marrow infiltration and strongly influences therapeutic strategies."
Fin de la cita.
saludos.

  

JAJA!!
Leete la misma informacion publicada por Victor en :
http://www.mieloma.com/v2/viewtopic.php?f=31&t=2902
fuente:
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum

  Es broma!!
Tambien esta en ingl?s, y es la misma fuente!..     


  asi que fui a google y he pedido la  traduccion del articulo:.
      He obtenido este resultado(peor todav?a!:        )

"Comparison of whole-body MR imaging and conventional X-ray examination in patients with multiple myeloma and implications for therapy." "Comparaci?n de cuerpo entero y de im?genes de RM convencionales de rayos X en el examen de los pacientes con mieloma m?ltiple y las implicaciones para la terapia".
Dinter DJ, Neff WK, Klaus J, B?hm C, Hastka J, Weiss C, Schoenberg SO, Metzgeroth G. Dinter DJ, Neff WK, Klaus J, B?hm C, Hastka J, Weiss C, Schoenberg SO, Metzgeroth G.

Department of Clinical Radiology and Nuclear Medicine, University Medical Center Manheim, Mannheim, Germany, Departamento de Cl?nica de Radiolog?a y Medicina Nuclear, Centro M?dico de la Universidad de Manheim, Mannheim, Alemania, .

Skeletal X-ray survey is the established method of diagnosis in patients with multiple myeloma; however, whole-body magnetic resonance imaging (wb-MRI) has become an important additional tool. Esquel?tico de rayos X de la encuesta es el m?todo de diagn?stico en pacientes con mieloma m?ltiple, sin embargo, todo el cuerpo de im?genes por resonancia magn?tica (RM-BM) se ha convertido en una importante herramienta adicional. The aim of this study was to compare the different patterns of infiltration on conventional X-ray examinations (X-ray survey) with findings from wb-MRI to subsequently determine the influence of wb-MRI on therapy changes. El objetivo de este estudio fue comparar los distintos modelos de infiltraci?n convencionales de rayos X de los ex?menes (de rayos X encuesta) con los resultados de la RM-WB para posteriormente determinar la influencia del Banco Mundial-RM en la terapia cambios. In 60 patients with a mean age of 65.1 +/- 11.7 years, wb-MRI examinations were correlated with a recent X-ray survey. En 60 pacientes con una edad media de 65,1 + / - 11,7 a?os, el Banco Mundial-ex?menes de resonancia magn?tica se correlaciona con los ?ltimos rayos X encuesta. The results were independently assessed by two radiologists and the patterns of infiltration were described in both modalities. Los resultados fueron evaluados independientemente por dos radi?logos y los patrones de infiltraci?n se describen en ambas modalidades. Subsequently, the disease was staged according to Salmon and Durie and Salmon and Durie PLUS. Posteriormente, la enfermedad se realiz? de acuerdo a Salm?n y Salm?n y Durie y Durie PLUS. Additionally, the influence of MRI on potential changes in therapy was assessed using a three-range Likert-type scale. Adem?s, la influencia de la RM sobre posibles cambios en la terapia se evalu? mediante una serie de tres tipo Likert de escala. In all, 480 skeletal regions were compared. En total, 480 fueron las regiones esquel?ticas en comparaci?n. In 183 skeletal regions, an increased degree of infiltration was identified on wb-MRI. En 183 regiones esquel?ticas, un mayor grado de infiltraci?n fue identificado en el BM-RM. Significant differences (p < 0.05) between the modalities could be found in the thorax, spine, pelvis, and both lower extremities. Diferencias significativas (p <0,05) entre las modalidades se puede encontrar en el t?rax, la columna vertebral, pelvis, y ambas extremidades inferiores. Based on wb-MRI, tumor stage was upgraded in 19 of the 60 patients using the Durie and Salmon PLUS classification. Sobre la base de BM-MRI, tumoral fue actualizado en 19 de los 60 pacientes utilizando el Durie y Salm?n PLUS clasificaci?n. In ten out of these 19 patients (42%), the wb-MRI result was essential for making the decision to initiate further therapy due to the degree of infiltration, extramedullary tumor extension, and/or further risk of fracture. En diez de estos 19 pacientes (42%), el BM-RM resultado fue esencial para tomar la decisi?n de iniciar la terapia m?s debido al grado de infiltraci?n, la extensi?n del tumor extramedular, y / o de mayor riesgo de fractura.
Whole-body MRI provides a more detailed assessment of the pattern of bone marrow infiltration and strongly influences therapeutic strategies." Todo el cuerpo RM proporciona una evaluaci?n m?s detallada de la estructura de la m?dula ?sea y la infiltraci?n influye fuertemente en estrategias terap?uticas ".
Fin de la cita. Fin de la cita.

JAJAJA!!
Un abrazo