Fuente y mas informacion:
jueves, 7 agosto, 2008 7:27 PM
De: "MMRF SmartBrief "
http://www.multiplemyeloma.org/

Blood. 2008 Jul 31
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Seven year median time to progression with thalidomide for smoldering myeloma: Partial response identifies subset requiring earlier salvage therapy for symptomatic disease
Barlogie B, van Rhee F, Shaughnessy JD Jr, Epstein J, Yaccoby S, Pineda-Roman M, Hollmig K, Alsayed Y, Hoering A, Szymonifka J, Anaissie E, Petty N, Kumar NS, Srivastava G, Jenkins B, Crowley J, Zeldis JB


Ann Hematol. 2008 Jul 31
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone
Klein U, Kosely F, Hillenga? J, Hundemer M, Schmitt S, Neben K, Moehler T, Hegenbart U, Ho AD, Goldschmidt H


Br J Haematol. 2008 Jul 31
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
The relationship between quality of response and clinical benefit for patients treated on the bortezomib arm of the international, randomized, phase 3 APEX trial in relapsed multiple myeloma
Niesvizky R, Richardson PG, Rajkumar SV, Coleman M, Rosi?ol L, Sonneveld P, Schuster MW, Irwin D, Stadtmauer EA, Facon T, Harousseau JL, Boral AL, Esseltine DL, Anderson KC, Blade J





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
jueves, 14 agosto, 2008 4:21 PM
De: "MMRF SmartBrief "
http://www.multiplemyeloma.org/



Clin Lymphoma Myeloma. 2008 Jun
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
An observational, retrospective analysis of retreatment with bortezomib for multiple myeloma
Conner TM, Doan QD, Walters IB, Leblanc AL, Beveridge RA


Clin Lymphoma Myeloma. 2008 Jun
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Thalidomide maintenance following high-dose melphalan with autologous stem cell support in myeloma
Chang JE, Juckett MB, Callander NS, Kahl BS, Gangnon RE, Mitchell TL, Longo WL


Clin Lymphoma Myeloma. 2008 Jun
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Features and risk factors of peripheral neuropathy during treatment with bortezomib for advanced multiple myeloma
El-Cheikh J, Stoppa AM, Bouabdallah R, de Lavallade H, Coso D, de Collela JM, Auran-Schleinitz T, Gastaut JA, Blaise D, Mohty M


Cancer. 2008 Aug 5
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
A multicenter, randomized clinical trial comparing zoledronic acid versus observation in patients with asymptomatic myeloma
Musto P, Petrucci MT, Bringhen S, Guglielmelli T, Caravita T, Bongarzoni V, Andriani A, D'Arena G, Balleari E, Pietrantuono G, Boccadoro M, Palumbo A; for the GIMEMA (Italian Group for Adult Hematologic Diseases)/Multiple Myeloma Working Party and the Italian Myeloma Network





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
jueves, 21 agosto, 2008
De: "MMRF SmartBrief "
http://www.multiplemyeloma.org/

Curr Opin Support Palliat Care. 2008 Sep
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
New drugs in multiple myeloma
Berenson JR, Yellin O


J Clin Oncol. 2008 Aug 18
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Analysis of Herpes Zoster Events Among Bortezomib-Treated Patients in the Phase III APEX Study
Chanan-Khan A, Sonneveld P, Schuster MW, Stadtmauer EA, Facon T, Harousseau JL, Ben-Yehuda D, Lonial S, Goldschmidt H, Reece D, Neuwirth R, Anderson KC, Richardson PG


Ann Oncol. 2008 Aug 9
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
Dimopoulos MA, Kastritis E, Bamia C, Melakopoulos I, Gika D, Roussou M, Migkou M, Eleftherakis-Papaiakovou E, Christoulas D, Terpos E, Bamias A





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Myeloma Minute - August 25, 2008
http://readtheminute.myeloma.org/

Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction
http://bloodjournal.hematologylibra.../full/112/4/990
Steven M. Devine, Ravi Vij, Michael Rettig, Laura Todt, Kiley McGlauchlen, Nicholas Fisher, Hollie Devine, Daniel C. Link, Gary Calandra, Gary Bridger, Peter Westervelt, and John F. DiPersio
Blood, 15 August 2008, Vol. 112, No. 4, pp. 990-998 (full text of article)

A freeway to stem cells?
http://bloodjournal.hematologylibra.../full/112/4/923
Alois Gratwohl, and Aleksandra Wodnar-Filipowicz
Blood, 15 August 2008, Vol. 112, No. 4, pp. 923-924.
A comment on Devine et al, listed above.

Bortezomib, doxorubicin and dexamethasone in advanced multiple myeloma
http://annonc.oxfordjournals.org/cgi/content/abstract/19/6/1160
A. Palumbo*, F. Gay, S. Bringhen, A. Falcone, N. Pescosta, V. Callea, T. Caravita, F. Morabito, V. Magarotto, M. Ruggeri, I. Avonto, P. Musto, N. Cascavilla, B. Bruno and M. Boccadoro*
Annals of Oncology 2008 19(6):1160-1165 (originally published online on March 6, 2008)

Thalidomide maintenance following high-dose melphalan with autologous stem cell support in myeloma.
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Chang JE, Juckett MB, Callander NS, Kahl BS, Gangnon RE, Mitchell TL, Longo WL.
Clin Lymphoma Myeloma. 2008 Jun;8(3):153-8

Multiple Myeloma, an update on diagnosis and treatment.
http://www.ncbi.nlm.nih.gov/pubmed/18637123?dopt=Abstract
Caers J, Vande Broek I, De Raeve H, Michaux L, Trullemans F, Schots R, Van Camp B, Vanderkerken K.
Eur J Haematol. 2008 Jul 11. [Epub ahead of print]

The role of high-dose chemotherapy followed by peripheral blood stem cell transplantation for the treatment of multiple myeloma.
http://www.ncbi.nlm.nih.gov/pubmed/18608872
Siddiqui M, Gertz M.*
Leuk Lymphoma. 2008 Apr 30:1-16.

Autologous stem cell transplantation in patients of 70 years and older with multiple myeloma: Results from a matched pair analysis.
http://www.ncbi.nlm.nih.gov/pubmed/18429054
Kumar SK, Dingli D, Lacy MQ, Dispenzieri A, Hayman SR, Buadi FK, Rajkumar SV*, Litzow MR, Gertz MA.*
Am J Hematol 2008 Aug;83(8):614-7.

Stem cell mobilization with cyclophosphamide overcomes the suppressive effect of lenalidomide therapy on stem cell collection in multiple myeloma
http://www.ncbi.nlm.nih.gov/pubmed/18429054
Mark T, Stern J, Furst JR, Jayabalan D, Zafar F, LaRow A, Pearse RN, Harpel J, Shore T, Schuster MW, Leonard JP, Christos PJ, Coleman M, Niesvizky R.
Biol Blood Marrow Transplant. 2008 Jul;14(7):795-8.

Seven year median time to progression with thalidomide for smoldering myeloma: Partial response identifies subset requiring earlier salvage therapy for symptomatic disease
http://bloodjournal.hematologylibra...64228v1?papetoc
Bart Barlogie*, Frits van Rhee, John D Shaughnessy, Jr, Joshua Epstein, Shmuel Yaccoby, Mauricio Pineda-Roman, Klaus Hollmig, Yazan Alsayed, Antje Hoering, Jackie Szymonifka, Elias Anaissie, Nathan Petty, Naveen S Kumar, Geetika Srivastava, Bonnie Jenkins, John Crowley*, and Jerome B. Zeldis
Blood published 31 July 2008, 10.1182/blood-2008-06-164228

Multiparameter flow cytometry remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation
http://bloodjournal.hematologylibra...59624v1?papetoc
Bruno Paiva, Maria-Belen Vidriales, Jorge Cervero, Gema Mateo, Jose J. Perez, Maria Angeles Montalban, Anna Sureda, Laura Montejano, Norma C. Gutierrez, Alfonso Garcia de Coca, Natalia de las Heras, Maria Victoria Mateos, Maria Consuelo Lopez-Berges, Raimundo Garcia-Boyero, Josefina Galende, Jose Hernandez, Luis Palomera, Dolores Carrera, Rafael Martinez, Javier de la Rubia, Alejandro Martin, Joan Blade*, Juan Jose Lahuerta, Alberto Orfao, and Jesus F. San Miguel*
Blood published 31 July 2008, 10.1182/blood-2008-05-159624

First thalidomide clinical trial in multiple myeloma: a decade
http://bloodjournal.hematologylibra...112/4/1035?etoc
Frits van Rhee, Madhav Dhodapkar, John D. Shaughnessy, Jr, Elias Anaissie, David Siegel*, Antje Hoering, Jerome Zeldis, Bonnie Jenkins, Seema Singhal*, Jayesh Mehta*, John Crowley*, Sundar Jagannath*, and Bart Barlogie*
Blood 2008;112 1035-1038

Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
http://bloodjournal.hematologylibra...112/4/1329?etoc
Yu-Tzu Tai, Myles Dillon, Weihua Song, Merav Leiba, Xian-Feng Li, Peter Burger, Alfred I. Lee, Klaus Podar, Teru Hideshima, Audie G. Rice, Anne van Abbema, Lynne Jesaitis, Ingrid Caras, Debbie Law, Edie Weller, Wanling Xie, Paul Richardson*, Nikhil C. Munshi*, Claire Mathiot, Herve Avet-Loiseau*, Daniel E. H. Afar, and Kenneth C. Anderson*
Blood 2008;112 1329-1337

Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors
http://bloodjournal.hematologylibra...112/4/1338?etoc
Sanjai Sharma and Alan Lichtenstein
Blood 2008;112 1338-1345

Validation of PDGFR{beta} and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib
http://bloodjournal.hematologylibra...112/4/1346?etoc
Addolorata Maria Luce Coluccia, Teresa Cirulli, Paola Neri, Domenica Mangieri, Maria Cristina Colanardi, Antonio Gnoni, Nicola Di Renzo, Franco Dammacco, Pierfrancesco Tassone, Domenico Ribatti, Carlo Gambacorti-Passerini, and Angelo Vacca
Blood 2008;112 1346-1356

Differential pattern of CD4+ and CD8+ T cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma
http://bloodjournal.hematologylibra...49393v1?papetoc
Oliver Charles Goodyear, Guy Pratt, Andrew McLarnon, Mark Cook, Karen Piper, and Paul Moss
Blood published 24 July 2008, 10.1182/blood-2008-04-149393

Effect of pathologic fractures on survival in multiple myeloma patients: a case control study
http://www.jeccr.com/content/27/1/11
Mehmet Sonmez, Tulin Akagun, Murat Topbas, Umit Cobanoglu, Bircan Sonmez, Mustafa Yilmaz, Ercument Ovali and Serdar Bedii Omay
Journal of Experimental & Clinical Cancer Research 2008, 27:11

The incidence of and risk factors for venous thromboembolism (VTE) and bleeding among 1514 patients undergoing hematopoietic stem cell transplantation: implications for VTE prevention
http://bloodjournal.hematologylibra.../112/3/504?etoc
David E. Gerber, Jodi B. Segal, M. Yair Levy, Joyce Kane, Richard J. Jones, and Michael B. Streiff
Blood 2008;112 504-510

Constitutive expression of IL-12R{beta}2 on human multiple myeloma cells delineates a novel therapeutic target
http://bloodjournal.hematologylibra.../112/3/750?etoc
Irma Airoldi, Claudia Cocco, Nicola Giuliani, Marina Ferrarini, Simona Colla, Emanuela Ognio, Giuseppe Taverniti, Emma Di Carlo, Giovanna Cutrona, Vittorio Perfetti, Vittorio Rizzoli, Domenico Ribatti, and Vito Pistoia
Blood 2008;112 750-759

Cyproheptadine displays preclinical activity in myeloma and leukemia
http://bloodjournal.hematologylibra.../112/3/760?etoc
Xinliang Mao, Sheng-ben Liang, Rose Hurren, Marcela Gronda, Sue Chow, G. Wei Xu, Xiaoming Wang, Reza Beheshti Zavareh, Nazir Jamal, Hans Messner, David W. Hedley, Alessandro Datti, Jeff L. Wrana, Yuanxiao Zhu, Chang-xin Shi, Kyle Lee, Rodger Tiedemann, Suzanne Trudel, A. Keith Stewart*, and Aaron D. Schimmer
Blood 2008;112 760-769

Familial Myeloma
http://www.ncbi.nlm.nih.gov/pubmed/18614782
Henry T. Lynch, M.D., Kelly Ferrara, M.S., Bart Barlogie, M.D., Ph.D*., Elizabeth A. Coleman, Ph.D., Jane F. Lynch, B.S.N., Dennis Weisenburger, M.D., Warren Sanger, Ph.D., Patrice Watson, Ph.D., Henry Nipper, Ph.D., Vinetta Witt, Ph.D., and Stephan Thom?, M.D.
N Engl J Med. 2008 Jul 10;359(2):152-7.

Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
http://annonc.oxfordjournals.org/cg...act/mdn554v1?ct
M. A. Dimopoulos*, E. Kastritis, C. Bamia, I. Melakopoulos, D. Gika, M. Roussou, M. Migkou, E. Eleftherakis-Papaiakovou, D. Christoulas, E. Terpos and A. Bamias
Annals of Oncology, doi:10.1093/annonc/mdn554

An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma
http://7thspace.com/headlines/28979...le_myeloma.html
Domenica Ronchetti, Marta Lionetti, Laura Mosca, Luca Agnelli, Adrian Andronache, Sonia Fabris, Giorgio Lambertenghi Deliliers and Antonino Neri
(from 7th Space)





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
August 28, 2008
De: "MMRF SmartBrief "
http://www.multiplemyeloma.org/

Br J Haematol. 2008 Aug 18
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
Characterisation of haematological profiles and low risk of thromboembolic events with bortezomib in patients with relapsed multiple myeloma
Lonial S, Richardson PG, San Miguel J, Sonneveld P, Schuster MW, Blad? J, Cavenagh J, Rajkumar SV, Jakubowiak AJ, Esseltine DL, Anderson KC, Harousseau JL


In Vivo. 2008 Jul-Aug
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
18F-FDG PET/CT in myeloma with presumed solitary plasmocytoma of bone
Nanni C, Rubello D, Zamagni E, Castellucci P, Ambrosini V, Montini G, Cavo M, Lodi F, Pettinato C, Grassetto G, Franchi R, Gross MD, Fanti S


Blood. 2008 Aug 19
http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum
IRF-4 functions as a tumor suppressor in early B-cell development
Acquaviva J, Chen X, Ren R





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Gracias Victor!
Cuantos "deberes" para el fin de semana!JAJA!!
Un abrazo