Fuente y mas informacion:
Thu, 27 Dec 2007 11:31:17 -0600 (CST)
De:    "MMRF SmartBrief "
http://www.multiplemyeloma.org/

    * Oncology (Williston Park). 2007 Nov
      Liposomal doxorubicin in combination with bortezomib for relapsed or refractory multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Ning YM, He K, Dagher R, Sridhara R, Farrell AT, Justice R, Pazdur R.

    * Leuk Res. 2007 Dec 12
      Phase II clinical trial of arsenic trioxide with liposomal doxorubicin, vincristine, and dexamethasone in newly diagnosed multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Hofmeister CC, Jansak B, Denlinger N, Kraut EH, Benson DM, Farag SS.

    * Best Pract Res Clin Haematol. 2007 Dec
      Supportive care in multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Ludwig H, Zojer N.





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Thu, 20 Dec 2007 13:02:28 -0600 (CST)
De:    "MMRF SmartBrief "
http://www.multiplemyeloma.org/

    * Blood. 2007 Dec 5
      CEP-18770: a novel orally-active proteasome inhibitor with a tumor-selective pharmacological profile competitive with bortezomib
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Piva R, Ruggeri B, Williams M, Costa G, Tamagno I, Ferrero D, Giai V, Coscia M, Peola S, Massaia M, Pezzoni G, Allievi C, Pescalli N, Cassin M, di Giovine S, Nicoli P, de Feudis P, Strepponi I, Roato I, Ferracini R, Bussolati B, Camussi G, Jones-Bolin S, Hunter K, Zhao H, Neri A, Palumbo A, Berkers C, Ovaa H, Bernareggi A, Inghirami G.

    * Clin J Oncol Nurs. 2007 Dec
      Clinical updates and nursing considerations for patients with multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Faiman B.

    * Leuk Lymphoma. 2007 Dec
      Combination of rituximab and oral melphalan and prednisone in newly diagnosed multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Baz R, Fanning S, Kunkel L, Gaballa S, Karam MA, Reed J, Kelly M, Hussein M.

    * Clin J Oncol Nurs. 2007 Dec
      Multiple myeloma and treatment-related thromboembolism: oncology nurses' role in prevention, assessment, and diagnosis
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Wiley KE.





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Thu, 6 Dec 2007 13:26:29 -0600 (CST)
De:    "MMRF SmartBrief "
http://www.multiplemyeloma.org/

    * Leukemia. 2007 Nov 29
      Do beta2 microglobulin levels affect survival of newly diagnosed myeloma patients with translocation t(4;14) or 17p13 deletion treated with conventional chemotherapy?
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Chng WJ, Jacobus S, Fonseca R.

    * J Immunother (1997). 2007 November/December
      Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum

    * Future Oncol. 2007 Dec
      PI3 kinase/AKT pathway as a therapeutic target in multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Harvey RD, Lonial S.

    * Hematol Oncol Clin North Am. 2007 Dec
      Role of stem cell transplantation
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Harousseau JL.





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Myeloma Minute - November 29, 2007
http://readtheminute.myeloma.org/



    * Lenalidomide plus Dexamethasone for Relapsed Multiple Myeloma in North America
http://content.nejm.org/cgi/content/short/357/21/2133
      Donna M. Weber, M.D., Christine Chen, M.D., Ruben Niesvizky, M.D., Michael Wang, M.D., Andrew Belch, M.D., Edward A. Stadtmauer, M.D., David Siegel, M.D., Ivan Borrello, M.D., S. Vincent Rajkumar, M.D., Asher Alban Chanan-Khan, M.D., Sagar Lonial, M.D., Zhinuan Yu, Ph.D., John Patin, M.S., Marta Olesnyckyj, R.N., Jerome B. Zeldis, M.D., Ph.D., Robert D. Knight, M.D., for the Multiple Myeloma (009) Study Investigators
      New England Journal of Medicine published 21 November 2007, Volume 357:2133-2142

    * Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy
http://bloodjournal.hematologylibra...02632v1?papetoc
      Yulia Nefedova, Daniel M Sullivan, Sophie C Bolick, William S Dalton,? and Dmitry I. Gabrilovich
      Blood published 26 November 2007, 10.1182/blood-2007-07-102632

    * Etanercept plus methylprednisolone as initial therapy for acute GVHD
http://bloodjournal.hematologylibra...12987v1?papetoc
      John E Levine, Sophie Paczesny, Shin Mineishi, Thomas Braun, Sung W? Choi, Raymond J Hutchinson, Dawn Jones, Yasser Khaled, Carrie L Kitko,? Daniel Bickley, Oleg Krijanovski, Pavan Reddy, Gregory Yanik, and? James L.M. Ferrara
      Blood published 27 November 2007, 10.1182/blood-2007-09-112987





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Myeloma Minute - November 13, 2007
http://readtheminute.myeloma.org/



    * BiRD (Biaxin(R)[clarithromycin]/Revlimid(R)[lenalidomide]/dexamethasone) combination therapy results in high complete- and overall-response rates in treatment-naive symptomatic multiple myeloma
http://bloodjournal.hematologylibra...90258v1?papetoc
      Ruben Niesvizky, David S. Jayabalan, Paul J. Christos, Jessica R. Furst, Tara Naib, Scott Ely, Jessica Jalbrzikowski, Roger N. Pearse, Faiza Zafar, Karen Pekle, April LaRow, Richard Lent, Tomer Mark, Hearn J. Cho, Tsiporah Shore, Jeffrey Tepler, John Harpel, Michael W. Schuster, Susan Mathew, John P. Leonard, Madhu Mazumdar, Selina
      Chen-Kiang, and Morton Coleman
      Blood published 7 November 2007, 10.1182/blood-2007-05-090258

    * MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts
http://bloodjournal.hematologylibra...10/10/3744?etoc
      Sonia Vallet, Noopur Raje, Kenji Ishitsuka, Teru Hideshima, Klaus Podar, Shweta Chhetri, Samantha Pozzi, Iris Breitkreutz, Tanyel Kiziltepe, Hiroshi Yasui, Enrique M. Ocio, Norihiko Shiraishi, Janice Jin, Yutaka Okawa, Hiroshi Ikeda, Siddhartha Mukherjee, Nileshwari Vaghela, Diana Cirstea, Marco Ladetto, Mario Boccadoro*, and Kenneth C. Anderson*
      Blood 2007;110 3744-3752

    * Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial
http://bloodjournal.hematologylibra...10/10/3557?etoc
      Paul G. Richardson*, Pieter Sonneveld*, Michael Schuster, David Irwin, Edward Stadtmauer, Thierry Facon, Jean-Luc Harousseau*, Dina Ben-Yehuda, Sagar Lonial, Hartmut Goldschmidt*, Donna Reece*, Jesus San Miguel*, Joan Blade*, Mario Boccadoro*, Jamie Cavenagh, Melissa Alsina, S. Vincent Rajkumar*, Martha Lacy, Andrzej Jakubowiak, William Dalton, Anthony Boral, Dixie-Lee Esseltine, David Schenkein, and Kenneth C. Anderson*
      Blood 2007;110 3557-3560

    * Amyloidosis: graviores morbos, asperis remedii
http://bloodjournal.hematologylibra...10/10/3490?etoc
      Jayesh Mehta*
      Blood 2007;110 3490-3491

    * Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem-cell transplantation
http://bloodjournal.hematologylibra...10/10/3561?etoc
      Vaishali Sanchorawala, Martha Skinner, Karen Quillen, Kathleen T. Finn, Gheorghe Doros, and David C. Seldin
      Blood 2007;110 3561-3563

    *
      Calreticulin expression in the clonal plasma cells of patients with systemic light-chain (AL-)amyloidosis is associated with response to high-dose melphalan
http://bloodjournal.hematologylibra...90852v1?papetoc
      Ping Zhou, Julie Teruya-Feldstein, Ping Lu, Martin Fleisher, Adam Olshen, and Raymond L. Comenzo*
      Blood published 2 November 2007, 10.1182/blood-2007-05-090852

    *
      RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome and multiple myeloma elicits immunological and clinical responses
http://bloodjournal.hematologylibra...99366v1?papetoc
      Michael Schmitt, Anita Schmitt, Markus T Rojewski, Jinfei Chen, Krzysztof Giannopoulos, Fei Fei, Yingzhe Yu, Marlies Gotz, Marta Heyduk, Gerd Ritter, Daniel E Speiser, Sacha Gnjatic, Philippe Guillaume, Mark Ringhoffer, Richard F Schlenk, Peter Liebisch, Donald Bunjes, Hiroshi Shiku, Hartmut Dohner, and Jochen Greiner
      Blood published 31 October 2007, 10.1182/blood-2007-07-099366





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Thu, 8 Nov 2007 13:18:02 -0600 (CST)
De:    "MMRF SmartBrief "
http://www.multiplemyeloma.org/

 Research Updates         

    * Leukemia. 2007 Nov 1
      Clinically relevant end points and new drug approvals for myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Anderson KC, Kyle RA, Rajkumar SV, Stewart AK, Weber D, Richardson P.

    * Clin Adv Hematol Oncol. 2007 Sep
      Complete remission of multiple myeloma
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Lonial S.

    * Cancer. 2007 Oct 31
      Cyclophosphamide plus dexamethasone is an efficient initial treatment before high-dose melphalan and autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of a randomized comparison with vincristine, doxorubicin, and dexamethasone
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Mellqvist UH, Lenhoff S, Johnsen HE, Hjorth M, Holmberg E, Juliusson G, Tangen JM, Westin J; for the Nordic Myeloma Study Group.

    * Blood. 2007 Nov 1
      Improved survival in multiple myeloma and the impact of novel therapies
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Kumar SK, Rajkumar SV, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Zeldenrust SR, Dingli D, Russell SJ, Lust JA, Greipp PR, Kyle RA, Gertz MA.





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Myeloma Minute - November 6, 2007
http://readtheminute.myeloma.org/



    * Chemotherapy and survival for patients with multiple myeloma: findings from a large nationwide and population-based cohort.
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Rohatgi N, Du XL, Coker AL, Moye LA, Wang M, Fang S.
      Am J Clin Oncol. 2007 Oct;30(5):540-8.

    * Improved survival in multiple myeloma and the impact of novel therapies
http://bloodjournal.hematologylibra...007-10-116129v1
      Shaji K Kumar, S. Vincent Rajkumar*, Angela Dispenzieri, Martha Q. Lacy, Suzanne R Hayman, Francis K Buadi, Steven R Zeldenrust, David Dingli, Stephen J Russell, John A. Lust, Philip R Greipp, Robert A Kyle*, and Morie A Gertz*
      Blood First Edition Paper, prepublished online November 1, 2007

    * Recent major improvement in long-term survival of younger patients with multiple myeloma
http://bloodjournal.hematologylibra...007-08-104984v1
      Hermann Brenner, Adam Gondos, and Dianne Pulte
      Blood First Edition Paper, prepublished online September 27, 2007





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
Myeloma Minute - October 25, 2007
http://readtheminute.myeloma.org/

    *  Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma
http://bloodjournal.hematologylibra...110/9/3112?etoc
      David Gonzalez, Mirjam van der Burg, Ramon Garcia-Sanz, James A. Fenton, Anton W. Langerak, Marcos Gonzalez, Jacques J. M. van Dongen, Jesus F. San Miguel*, and Gareth J. Morgan*
      Blood 2007;110 3112-3121

    * Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma
http://bloodjournal.hematologylibra...110/9/3281?etoc
      Deborah J. Kuhn, Qing Chen, Peter M. Voorhees, John S. Strader, Kevin D. Shenk, Congcong M. Sun, Susan D. Demo, Mark K. Bennett, Fijs W. B. van Leeuwen, Asher A. Chanan-Khan, and Robert Z. Orlowski
      Blood 2007;110 3281-3290

    *

      Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma
http://bloodjournal.hematologylibra...110/9/3291?etoc
      Matthew W. Jenner, Paola E. Leone, Brian A. Walker, Fiona M. Ross, David C. Johnson, David Gonzalez, Laura Chiecchio, Elisabet Dachs Cabanas, Gian Paolo Dagrada, Mathew Nightingale, Rebecca K. M. Protheroe, David Stockley, Monica Else, Nicholas J. Dickens, Nicholas C. P. Cross, Faith E. Davies, and Gareth J. Morgan
      Blood 2007;110 3291-3300

    * Premature cardiovascular disease after allogeneic hematopoietic stem-cell transplantation
http://bloodjournal.hematologylibra...110/9/3463?etoc
      Andre Tichelli, Christoph Bucher, Alicia Rovo, Georg Stussi, Martin Stern, Michael Paulussen, Jorg Halter, Sandrine Meyer-Monard, Dominik Heim, Dimitrios A. Tsakiris, Barbara Biedermann, Jakob R. Passweg, and? Alois Gratwohl
      Blood 2007;110 3463-3471

    * Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial
http://www.docguide.com/news/conten...t_uids=17920916
      Facon T., Mary JY, Hulin C, Benboubker L, Attal M, Pegourie B, Renaud M, Harousseau JL, Guillerm G, Chaleteix C, Dib M, Voillat L, Maisonneuve H, Troncy J, Dorvaux V, Monconduit M, Martin C, Casassus P, Jaubert J, Jardel H, Doyen C, Kolb B, Anglaret B, Grosbois B, Yakoub-Agha I, Mathiot C, Avet-Loiseau H; Intergroupe Francophone du Myélome.
      Lancet. 2007 Oct 6;370(9594):1209-18.

    * High Incidence of Invasive Aspergillosis Associated with Intestinal Graft-versus-Host Disease following Nonmyeloablative Transplantation.
http://www.ncbi.nlm.nih.gov/sites/e...Pubmed_RVDocSum
      Labbé AC, Su SH, Laverdière M, Pépin J, Patiño C, Cohen S, Kiss T, Lachance S, Sauvageau G, Busque L, Roy DC, Roy J.
      Biol Blood Marrow Transplant. 2007 Oct;13(10):1192-200. Epub 2007 Aug 3





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Fuente y mas informacion:
MYELOMA MINUTE - July 30, 2007
http://readtheminute.myeloma.org/

    * Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma
http://bloodjournal.hematologylibra...69625v1?papetoc
      David Gonzalez, Mirjam van der Burg, Ramon Garcia-Sanz, James A. Fenton, Anton W Langerak, Marcos Gonzalez, Jacques J.M. van Dongen, Jesus F. San Miguel*, and Gareth J Morgan*
      Blood published 18 July 2007, 10.1182/blood-2007-02-069625

    * Incidence, risk factors and management of osteonecrosis of the jaw in patients with multiple myeloma: a single-centre experience in 303 patients
http://www.blackwell-synergy.com/do...41.2006.06230.x
      Kostas Zervas, Evgenia Verrou, Zisis Teleioudis, Konstantinos Vahtsevanos, Anastasia Banti, Dimitra Mihou, Dimitris Krikelis and Evangelos Terpos
      British Journal of Haematology 134 (6), 620?623

  

    * Anti-{beta}2-microglobulin monoclonal antibodies induce apoptosis in myeloma cells by recruiting MHC class I to and excluding growth and survival cytokine receptors from lipid rafts
http://bloodjournal.hematologylibra...94417v1?papetoc
      Jing Yang, Xiang Zhang, Ji Wang, Jianfei Qian, Liang Zhang, Michael Wang, Larry W. Kwak, and Qing Yi
      Blood published 20 July 2007, 10.1182/blood-2007-06-094417

    * High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis
http://bloodjournal.hematologylibra.../110/3/827?etoc
      Frits van Rhee, Vanessa Bolejack, Klaus Hollmig, Mauricio Pineda-Roman, Elias Anaissie, Joshua Epstein, John D. Shaughnessy, Jr, Maurizio Zangari, Guido Tricot*, Abid Mohiuddin, Yazan Alsayed, Gail Woods, John Crowley*, and Bart Barlogie*
      Blood 2007;110 827-832





____________
Un saludo
Victor Quesada
Webmaster y Administrador de Mieloma.com

Guia de Uso - http://www.mieloma.com/ayuda/

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.