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Mieloma Novedades en investigacion noviembre 2006 (1)

Fuente y mas informacion:

Myeloma Minute - November 11, 2006
http://readtheminute.myeloma.org/


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      When "the same" is really "different"
http://www.bloodjournal.org/cgi/con...ourcetype=HWCIT
      Sagar Lonial
      Blood 2006;108 3233-3234

    * Exciting new agents in multiple myeloma
http://www.bloodjournal.org/cgi/con...ourcetype=HWCIT
      Giampaolo Merlini
      Blood 2006;108 3235-3236

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      Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
http://www.bloodjournal.org/cgi/con...ourcetype=HWCIT
      Michel Attal*, Jean-Luc Harousseau*, Serge Leyvraz, Chantal Doyen, Cyrille Hulin, Lofti Benboubker, Ibrahim Yakoub Agha, Jean-Henri Bourhis, Laurent Garderet, Brigitte Pegourie, Charles Dumontet, Marc Renaud, Laurent Voillat, Christian Berthou, Gerald Marit, Mathieu Monconduit, Denis Caillot, Bernard Grobois, Herve Avet-Loiseau*, Philippe Moreau, and Thierry Facon*, for the Inter-Groupe Francophone du Myelome (IFM)
      Blood 2006;108 3289-3294

    * Aggresome induction by proteasome inhibitor bortezomib and {alpha}-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells
http://www.bloodjournal.org/cgi/content/abstract/108/10/3441
      Laurence Catley, Ellen Weisberg, Tanyel Kiziltepe, Yu-Tzu Tai, Teru Hideshima, Paola Neri, Pierfrancesco Tassone, Peter Atadja, Dharminder Chauhan, Nikhil C. Munshi, and Kenneth C. Anderson*
      Blood 2006;108 3441-3449

    * A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
http://www.bloodjournal.org/cgi/content/abstract/108/10/3458
      Paul G. Richardson*, Emily Blood, Constantine S. Mitsiades, Sundar Jagannath*, Steven R. Zeldenrust, Melissa Alsina, Robert L. Schlossman, S. Vincent Rajkumar*, K. Raman Desikan, Teru Hideshima, Nikhil C. Munshi, Kathleen Kelly-Colson, Deborah Doss, Mary L. McKenney, Svetlana Gorelik, Diane Warren, Andrea Freeman, Rebecca Rich, Anfang Wu, Marta Olesnyckyj, Kenton Wride, William S. Dalton, Jerome Zeldis, Robert Knight, Edie Weller, and Kenneth C. Anderson*
      Blood 2006;108 3458-3464

    * MIP-1{alpha} (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma
http://www.bloodjournal.org/cgi/content/abstract/108/10/3465
      Esther Masih-Khan, Suzanne Trudel, Carla Heise, Zhihua Li, Joshua Paterson, Vincent Nadeem, Ellen Wei, David Roodman*, Jaime O. Claudio, P. Leif Bergsagel*, and A. Keith Stewart*
      Blood 2006;108 3465-3471

    * Thrombotic thrombocytopenic purpura associated with renal failure after autologous transplantation for multiple myeloma successfully treated with rituximab.
http://www.blackwell-synergy.com/do...09.2006.00758.x
      Gallerani E, Lerch E, Romagnani E, Stathis A, Giardelli G, Zwhalen H, Marone C, Cavalli F.
      European Journal of Haematology; Volume 77, Page 527-December 2006

    * Low tolerance and high toxicity of thalidomide as maintenance therapy after double autologous stem cell transplant in mutliple myeloma patients
http://www.blackwell-synergy.com/do...earch=allfield:(%22Low+tolerance+and+high+toxicity+of+thalidomide+as+maintenance+therapy+after+double+autologous+stem+cell+transplant+in+mutliple+myeloma+patients.%22)
      Martino M, Console G, Callea V, Stelitano C, Massara E, Irrera G, Messina G, Morabito F, Iacopino P.
      European Journal of Haematology; doi:10.1111/j.1600-0609.2006.00774.

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      Chaetocin, a promising new anti-myeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress
http://www.bloodjournal.org/cgi/con...006-07-027326v1
      Crescent R Isham, Jennifer D Tibodeau, Wendy Jin, Ruifang Xu, Michael M Timm, and Keith C Bible
      Blood published 7 November 2006, 10.1182/blood-2006-07-027326





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Guia de Uso - http://www.mieloma.com/v2/uso-del-foro-vf27.html

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

Mieloma Novedades en investigacion noviembre 2006 (1)

Fuente y mas informacion:

The Myeloma Minute - November 3, 2006
http://readtheminute.myeloma.org/


    *

      Thalidomide, dexamethasone, and pegylated liposomal  doxorubicin (ThaDD) for patients older than 65 years with newly diagnosed  multiple myeloma
http://www.bloodjournal.org/cgi/content/abstract/108/7/2159

      Offidani M, Corvatta L, Piersantelli MN, Visani G, Alesiani F,  Brunori M,Galieni P, Catarini M, Burattini M, Centurioni R, Ferranti M, Rupoli S,Scortechini AR, Giuliodori L, Candela M, Capelli D, Montanari M, Olivieri A,  Poloni A, Polloni C, Marconi M, Leoni P.
      Blood, 1 October 2006, Vol. 108, No. 7, pp. 2159-2164

    * Long-term outcome results of the first tandem autotransplant trial for multiple myeloma
http://www.blackwell-synergy.com/do...2006.06271.x?ai
      Bart Barlogie*, Guido J. Tricot*, Frits van Rhee, Edguardo Angtuaco, Ron Walker, Joshua Epstein, John D. Shaughnessy, Sundar Jagannath*, Vanessa Bolejack, Jennifer Gurley, Antje Hoering, David Vesole*, Raman Desikan, David Siegel*, Jayesh Mehta*, Seema Singhal*, Nikhil C. Munshi, Madhav Dhodapkar, Bonnie Jenkins, Michel Attal*, Jean-Luc Harousseau*, John Crowley*
      British Journal of Haematology; Volume 135, Issue 2, 2006 Oct1, Page 158

    *

      Low power laser in the prevention of induced oral mucositis in bone marrow transplantation patients: a randomized trial
http://www.bloodjournal.org/cgi/con...006-07-035022v1
      Heliton Spindola Antunes, Alexandre Melo de Azevedo, Luiz Fernando da Silva Bouzas, Carlos Alberto Esteves Adao, Claudia Tereza Pinheiro, Renato Mayhe, Lucia Helena Pinheiro, Renato Azevedo, Valkiria D'Aiuto de Matos, Pedro Carvalho Rodrigues, Isabele Avila Small, Renato Amaro Zangaro, and Carlos Gil Ferreira
      Blood published 19 October 2006, 10.1182/blood-2006-07-035022

    * Efficacy and safety of melphalan, arsenic trioxide and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: a prospective, multicentre, phase II, single-arm study
http://www.ingentaconnect.com/conte...000002/art00007
      James R. Berenson*, Ralph Boccia, David Siegel*, Marek Bozdech, Alberto Bessudo, Edward Stadtmauer, J. Talisman Pomeroy, Ronald Steis, Marshall Flam, Jose Lutzky, Syed Jilani, Joseph Volk, Siu-Fun Wong, Robert Moss, Ravi Patel, Delina Ferretti, Kit Russell, Robert Louie, Howard S. Yeh, Regina A. Swift
      British Journal of Haematology; Volume 135, Issue 2, 2006 Oct1, Page 174

    * Antibody-based inhibition of DKK1 suppresses tumor- induced bone resorption and multiple myeloma growth in-vivo
http://www.bloodjournal.org/cgi/con...47712v1?papetoc
      Shmuel Yaccoby, Wen Ling, Fenghuang Zhan, Ronald Walker, Bart Barlogie*, and John D Shaughnessy, Jr
      Blood published 26 October 2006, 10.1182/blood-2006-09-047712

    * Diabetes, hypertension and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplant survivor study
http://www.bloodjournal.org/cgi/con...22335v1?papetoc
      K. Scott Baker, Kirsten K Ness, Julia Steinberger, Andrea Carter, Liton Francisco, Linda J Burns, Charles Sklar, Stephen Forman, Daniel J. Weisdorf, James G Gurney, and Smita Bhatia
      Blood published 17 October 2006, 10.1182/blood-2006-05-022335





____________
Guia de Uso - http://www.mieloma.com/v2/uso-del-foro-vf27.html

Ser feliz no significa que todo sea perfecto, quiere decir que has decidido seguir adelante pese a las dificultades.

UAUUUU!!!
Cuantas noticias!!!Es un bombardeo!!!!   
Cuantos "deberes"!!
Muchas gracias!!!